Buy MOTS-c Research Peptide
MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA, within the 12S ribosomal RNA gene. We supply it as a lyophilized powder at 99%+ purity, verified by independent HPLC and mass spectrometry testing, in 10, 20 and 40 mg vials. Every order ships free with tracking from California. For laboratory research use only.
MOTS-c Vial Sizes and Prices
| Vial size | Price | Cost per mg | Add to cart |
|---|---|---|---|
| 10mg | $40.00 | $4.00 | Add to cart |
| 20mg | $60.00 | $3.00 | Add to cart |
| 40mgLowest cost per mg | $90.00 | $2.25 | Add to cart |
What MOTS-c Is
The name abbreviates “mitochondrial open reading frame of the 12S rRNA type-c”. MOTS-c is one of a small group of mitochondrial-derived peptides identified through analysis of short open reading frames in the mitochondrial genome, and it was first reported in 2015. Its sequence is Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg.
Published work characterises its translocation to the nucleus under metabolic stress, its interaction with the folate cycle and the associated activation of the AMPK pathway, and its regulation of nuclear gene expression in cultured cells and animal models.
MOTS-c Specifications
| Compound | MOTS-c |
|---|---|
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (MRWQEMGYIFYPRKLR) |
| Length | 16 amino acids |
| Origin | Encoded in the mitochondrial 12S rRNA gene (MT-RNR1) |
| CAS number | 1627580-64-6 |
| Molecular formula | C101H152N28O22S2 |
| Molecular weight | 2174.6 g/mol |
| Form | Lyophilized powder |
| Purity | 99%+ (HPLC/MS) |
| Storage | Store lyophilized at −20 °C, protected from light |
| Vial sizes | 10, 20 and 40 mg |
Choosing a MOTS-c Vial Size
Every size is the same compound supplied to the same specification; the sizes differ only in how much material each vial holds. Larger vials carry a lower cost per mg, and the table above shows the current figure for each size. Smaller vials suit pilot work, or study designs that call for several separately opened vials rather than one large one.
MOTS-c and Related Mitochondrial Research Compounds
MOTS-c is often studied alongside other compounds used in mitochondrial research, including NAD+ and SS-31. Our overview of mitochondrial-derived peptides covers the wider peptide family that MOTS-c belongs to.
MOTS-c Research Guides
Quality, Storage and Shipping
MOTS-c is supplied as a lyophilized powder at 99%+ purity, with identity and purity verified by independent HPLC and mass spectrometry testing; how we verify peptide purity explains the process. Store vials at −20 °C, protected from light. Orders are packed and dispatched from California by UPS or USPS with tracking, and shipping is free on every order. Contact us for testing documentation relating to a specific order.
Frequently Asked Questions
What is MOTS-c?
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA gene. It is one of a small group of mitochondrial-derived peptides and was first reported in 2015.
What is a mitochondrial-derived peptide?
A peptide encoded by a short open reading frame in mitochondrial DNA rather than in the nuclear genome. MOTS-c is encoded within the 12S rRNA gene of the mitochondrial genome.
What sizes of MOTS-c are available?
MOTS-c is supplied in several lyophilized vial sizes. The table at the top of this page lists every size with its current price and cost per mg, and each size also has its own product page.
What purity is the MOTS-c supplied at?
It is supplied as a lyophilized powder at 99%+ purity, verified by independent HPLC and mass spectrometry testing.
How should MOTS-c be stored?
Store the lyophilized powder at −20 °C and protect it from light.
Is this MOTS-c for human use?
No. It is supplied strictly for laboratory research. It is not intended for human or veterinary use, diagnosis, treatment or consumption.
Where do orders ship from?
All orders are dispatched from California by UPS or USPS with tracking. Shipping is free on every order.
For Research Use Only
This material is intended strictly for laboratory and research purposes. It is not intended for human or veterinary use, diagnosis, treatment, or consumption. By purchasing, the buyer confirms they are a qualified researcher and agrees to handle this product in compliance with all applicable regulations.