Description
ARA-290 | Erythropoietin-Derived Peptide – Research Peptide
ARA-290, also known as cibinetide, is a synthetic 11-amino-acid peptide derived from the helix B domain of erythropoietin (EPO). The sequence corresponds to a region of the EPO molecule that is not involved in binding the classical erythropoietin receptor, which means it lacks the erythropoietic activity of the parent hormone.
Research has characterised its interaction with a heteromeric complex formed from the EPO receptor and the beta-common receptor subunit (CD131). Studies have examined downstream signaling associated with this complex and its influence on cytokine and signaling marker expression in cultured systems, alongside work confirming that ARA-290 does not stimulate red blood cell production in model systems — the property that distinguishes it from erythropoietin itself.
Common research applications: EPO receptor/CD131 signaling, cytokine signaling research, and erythropoietin structure-function studies.
Specifications
| Compound | ARA-290 (Cibinetide) |
|---|---|
| Quantity | 10mg per vial |
| Purity | 99%+ (HPLC/MS) |
| Form | Lyophilized powder |
| Storage | Store lyophilized at minus 20 C, protect from light. |
Frequently Asked Questions
What is ARA-290?
ARA-290, also called cibinetide, is a synthetic 11-amino-acid peptide derived from the helix B domain of erythropoietin, lacking the erythropoietic activity of the parent hormone.
What is ARA-290 studied for?
Research applications include EPO receptor/CD131 signaling, cytokine signaling research and erythropoietin structure-function studies. All work is laboratory research only.
What purity is ARA-290 10mg supplied at?
It is supplied as lyophilized powder at 99%+ purity, verified by independent HPLC and mass spectrometry testing.
For Research Use Only
This material is intended strictly for laboratory and research purposes. It is not intended for human or veterinary use, diagnosis, treatment, or consumption. By purchasing, the buyer confirms they are a qualified researcher and agrees to handle this product in compliance with all applicable regulations.
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